90% of the body's creatine exists in muscle and most of the creatine phosphate in the form of existence. Creatine phosphate stripped phosphate generated creatinine, which excluded the urine is the urine creatinine. Of days of normal urine creatinine excretion is fairly stable, adult males emissions for the 1.0 ~ 1.8g, females 0.7 ~ 1.0g, and not subject to the impact of food protein content and urine output. 24h per kg body weight discharge of urine creatinine in mg number called the coefficient of urinary creatinine, a normal creatinine coefficient as follows: 18 male and 32 female 10 to 25. Athlete's urine creatinine coefficient is higher than normal, usually 25 to 40 different projects athletes’ urine creatinine coefficient is also different, for training athletes in strength and speed programs muscular, urinary creatinine coefficient is also high, and the daily urinary creatinine excretion is highly correlated with athletic performance.
The normal range of urinary creatinine values
8.4-1 3.25mmol/24 hour urine or and 40 mg / dl, to 130 mg / dl, it is normal.
Urine creatinine clinical significance
Increased: seen in acromegaly, gigantism, diabetes, infection, hypothyroidism, eating meat, exercise, intake of drugs (such as vitamin C, L-dopa, methyldopa, etc.). Reduction: seen in acute or chronic renal insufficiency, severe congestive heart failure, hyperthyroidism, anemia, muscular dystrophy, leukemia, vegetarians, and taking male hormones, thiazide drugs, etc.. Formula (Formula): C4H7N3O molecular weight (Molecular Weight): 113.1 CAS No.: 60-27-5
