What are the Symptoms and Complications of High Creatinine

Creatinine is a waste product in the blood that results from energy metabolism of muscle, which is transported in the bloodstream to the kidneys where it is then filtered and excreted from the body in urine. This chemical by-product of muscle metabolism is produced by creatine, and author and doctor of internal medicine Siamak Nabili states that around 2 percent of creatine in the body is transformed into creatinine on a daily basis. Creatinine is important because it is an indicator of kidney function; thus, decreased renal filtering and disposal (urine) may be reflected if the level of this waste product is high.
What are the general symptoms of high creatinine
With increasing creatinine levels, some possible signs may include a low-grade fever, fatigue, lethargy or a generalized sense of malaise. Loss of appetite and changes in weight may be identified. Dehydration may be present as well as headache complaints, and shortness of breath or problems with breathing. Also, a change in mental state may be noticed, for example, the individual may appear confused or disoriented.
What are the specific symptoms of high creatinine
An individual may present with decreased output of urine (oliguria) and urine may appear dark in color. Edema or puffiness such as in the face and around the eyes or other areas may be found upon examination. Additionally, the individual may report pain occurring in the lower back or lumbar region.
What are the complications of high creatinine level
Long time persistent high level of creatinine will cause a series of complications such as hyperkalaemia, hyperuricemia, hyperlipidemia, hypoalbuminemia, metabolic acidosis and disorders and imbalances in many other systems.