2012年8月16日星期四

Does High Creatinine Level must Be Related to Kidney Diseases

Creatinine is a product of muscle metabolism in the human body, 20g each muscle metabolism can produce 1mg creatinine, creatinine is an important part of the glomerular (kidney) filtration excreted from the two kinds of exogenous and endogenous serum creatinine, meat food product of the in vivo metabolism of exogenous creatinine; endogenous creatinine is muscle tissue in vivo metabolic product of muscle metabolism in the body and no major changes in the stability of the meat food intake., creatininegenerated will be relatively constant.
Clinical detection of serum creatinine is one of the common understanding of renal creatinine is how it goes? Endogenous creatinine is the production of human muscle metabolism: objects in the muscle, creatine, mainly through the irreversible non-enzymatic dehydration reaction to the formation of creatinine slowly, and then released into the bloodstream, with the urinary excretion of serum creatinine and total body muscle are closely related and less susceptible to diet shadow. creatinine small molecules, kidney / j the ball filter However, very little absorption in the renal tubules, creatinine, daily body produces almost all of the urine, are generally not subject to urine output affect renal insufficiency, creatinine, harmful toxins accumulate in the body. normal plasma creatinine The upper limit of about 100 micromoles / liter.

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