2013年8月12日星期一

What You May Have After Getting Polycystic Kidney Disease


In the early stage of Polycystic Kidney Disease, the size of kidneys may be normal or slightly larger. As the patients grow older, their cysts increase and more and more cysts appear. For most of the cases, when cysts enlarge to considerable extend, a series of symptoms will appear.
Ⅰ. Renal enlargement. The size of two kidneys is different due to the inconformity of the development of renal cysts. In the end stage, kidneys take up the entire abdominal cavity. In kidneys, there are so many cysts, which make kidney show as irregular shape and when we touch kidney parts, we feel it hard.
Ⅱ. Kidneys pain has significant meaning for diagnose Polycystic Kidney Disease, which usually manifest as dull pain and pressure on the lower back, sometimes, this pain may show as sharp pain and bellyache. The exacerbation of Kidneys pain can result from physical activity, long time walking and sitting. A bed rest can relieve this pain. Beside, renal hemorrhage, stone move and renal infection all are the causes of sudden pain of kidneys.
Ⅲ. More than half of the patients with Polycystic Kidney Disease have microscopic hematuria, which result from the angiorrhexis of cyst wall. Blood clots can cause pain when they flow through ureter. Hematuria is usually accompanied by proteinuria and leucocyturia, and during this period, urine protein is less than one gram per day. As the occurance of renal infection, pyuria and hematuria aggravate, meanwhile lower back pain is accompanied by fever.
Ⅳ. High blood pressure is the common performance of Autosomal Dominantl Polycystic Kidney Disease. Before the increase of serum creatinine, about half of patients with Polycystic Kidney Disease have high blood pressure. The occurance of high blood pressure among patients with Chronic Kidney Disease affects the prognosis of Polycystic Kidney Disease directly, that means if patients with Polycystic Kidney Disease have high blood pressure, their cysts will grow fast and this has a bad influence on the prognosis of Polycystic Kidney Disease.
Ⅴ. Renal insufficiency is inevitable for patients with Polycystic Kidney Disease and it seldom appears before patients younger than forty. About half of the patients who are seventy years old have renal function. however, if high blood pressure appears in patients with Polycystic Kidney Disease, then the process developing to renal failure will be shortened.
Ⅵ. Polycystic liver. The incidence of Polycystic Liver among patients who have been found with Autosomal Dominantl Polycystic Kidney Disease in their middle age is fifty percent. The appearance of Polycystic Liver is usually ten years later than Polycystic Kidney Disease.

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