2013年1月7日星期一

Immunotherapy for Treating Kidney Failure


Immunotherapy is the latest treatment for kidney failure. Here is the brief introduction of immunotherapy and it can be divided into 5 steps.
Firstly, Immune diagnosis
Why we can not get a good effect after having tried many therapies in treating kidney disease? why does kidney disease relapse easily? That is because we don't find the reason of kidney disease. so in this step, we should find out the harmful substances which cause damage to kidneys, which part of our kidney is damaged, is glomerulis or renal tubules? Our hospital has brought the most advanced equipment to do the special tests, like lymphocyte subsets which can judge patient's immune function; toxins in urine, which can tell us what kinds of toxins are accumulated in patient's body. These toxins may contain uric acid, creatinine, b2-microglobulin, CYS-C, retinol binding protein, homocysteine, parathyroid hormone. If patients have protein in urine, we also can judge which type of protein it is by urinary protein electrophoresis, then we can offer proper treatment schedule.
Secondly, Immune clearance
After finding out the harmful substances in our body, we should clear them. During this step, our hospital can clear the harmful substances (containing micromolecule substances, middle molecular substances, and macromolecules) with the help of many kinds of blood purification equipment, like immunosprption technics, plasma exchange and so on. Then the further damage to our kidneys and other organs can be stopped.
Thirdly, Immune blocking:
The above steps of treatment only aim at the harmful substances in our blood, and has no effect on the harmful substances deposited in kidneys, because there are specific attachment region on the face of kidneys, so when the harmful substances move to kidneys with the blood circulation, they will deposit in kidney, and cause imflammatory reaction. so in this step,we will use some specific immunosuppressive agents to block the reaction. But in western medicine, immunosuppressive agents are also adopted commonly, why it can not get a good therapeutic effect, the reason is that the kinds and quantity of harmful substances are not known, so doctors are often not sure the dose of medicine.
Fourth, Immune regulation
During this step of treatment, we will solve the deposition of harmful substances in kidneys. When our kidney is damaged, the blood flow volume in kidneys will reduce, so our hospital will use Micro-Chinese Medicine Osmotherapy to increase the blood flow volume in kidneys. You may have heard of Chinese medicine (Chinese herbs) before. Here only a simple affix “Micro-“is added before it, but it means a lot improvement in treating kidney disease. Traditional Chinese herbs are oral medicine. Firstly, they burden the kidneys, because the kidney is the organ responsible for filtrating fluid. Secondly, most of Chinese herbs decoction is bitter to drink. Many patients cannot bear them. Lastly, the rate of sorption by kidneys is very low, for it arrives at renal lesions through many tracts, such as digestive tract and gastrointestinal tract.
However, micro-Chinese Medicine Osmotherapy is different from traditional Chinese herbal medicine. Here, Chinese herbs are superfinely shattered into powder and packaged in a sack. When used, the sack should be soaked in the special penetrant for around two hours and then be heated for one hour or so. After all is ready, patients just need to lie in bed with two sacks attached to renal regions. What’s more, the sacks are connected with an osmosis device, the mechanism of which is to promote permeation of medicine by vibration indirectly controlled by electron pulse. In this way, the ingredients of Chinese medicine can efficiently permeate into the renal lesions, realizing the goal of treating kidney disease effectively. Patients would feel massaged during the treatment, very comfortable. Usually this treatment is given 2-3times every day and 45mins each time. Specifically speaking, Micro-Chinese Medicine can dilate blood vessels and decrease blood coagulation, thus improving blood circulation of kidneys. In addition, it can also decrease inflammatory reaction and degrade extracellular matrixes (ECM) both of which contribute to fibrosis of renal functional cells. In this way, Micro-Chinese Medicine can effectively prevent fibrosis and thereby stop kidney disease from progressing.
Fifth, Immune reconstruction
As we know, the reason of kidney disease is damaged immune system and low immunity, so if we want to avoid the relapse of kidney disease, we should to rebuild our immune system and improve our immunity.
Though it can benefit kidney patients a lot, it can not recover all your kidney functions. But so long as certain parts of kidney functions are improved, that can help you avoid dialysis, improve life quality and prolong life expectancy.
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