How Does Herbal Medicines Treat PKD

I will introduce you some information about the treatment with Herbal medicines. These infromation can help you know how PKD influence kidneys and how to use Herbal medicines to treat it step by step. Hope you can read the following information.
When the kidney tissues are invaded by inflamation, the kidney tubules epithelial will appear phenotype transformation and then the permeability of cyst wall decreases so that the cyst liquid secreted by cyst wall can not be discharged out of human body. Then the cyst liquid will accumulate into the cyst which will lead to the increase in size of cysts along with the time passing by. Cysts will suppress the capillaries in kidneys, which will increase the inner pressure of blood vessels. Then red blood cells and protein with negative charge will be leaked out from blood vessels because of the damage of barrier function. Bigger and bigger pressure to kidney ti
ssues can lead to ischemia and anoxia, thus leading to renal anemia at last. So the key point to treat Polycystic Kidney Disease is to control and shrink the size of cysts and supply new nephrons to play renal function which should have been done by those necrotic nephrons.
As we clearly research the pathological change of cysts, we renovate MicroChinese Medicine Osmotherapy based on Traditional Chinese Medicine. This therapy possesses two curative effects, the first one is: expand the vessels on thevascular wall surround the cysts, accelerate the blood circulation of cyst wall, promote the permeability of cyst wall, promote the inner press decrease of cyst wall vessels, reverse the differential pressure caused by intravascular pressure higher than intracapsular pressure,
accelerate the vessels re-sorption of the cyst liquid. The second one is: the active substance of Chinese Medicine can restrain the secretion of cyst wall epithelial cell; prevent the continuous expanding of bursa wall vessels and cyst. This therapy fundamentally controls the enlargement of cysts and repairs the damaged renal nephrons.
After you read the above information, I hope you will know what is the best treatment for Polycystic Kidney Disease. At the very beginning, patients with PKD don't have high creatinine or kidney function damage. If high creatinine and hypertension occur, it means kidney function begin to be damaged. I hope you can find the size of your kidneys and cysts. These information can judge your illness history.

PKD, High Creatinine of 5, High Blood Pressure

Illness description: I have PKD and both kidneys are affected. I have now high serum creatinine of 5, please advise options available. I also have high blood pressure and now am taking antihypertensive.
Illness analysis: High creatinine level means that the cysts have begin to affect your kidney functions.
PKD (polycystic kidney disease) is a kind of genetic disease and as the age increases, the cysts will become bigger and bigger. And our kidney also can be damaged. it has various complications, like backpain, abdominal mass (enlarged kidney), hematuresis, hypertension, cyst infection, in the end stage, patients may have hard breathing, nausea, vomit etc. In addition, many organs will be involved, like liver, pancreas. Patients may also some cardiovascular disease. The continuous growth of cysts can oppress kidney, damage kidney function.
Your cysts have been quite big, do you have back pain? Blood in urine?
High blood pressure is a common symptom in Polycystic Kidney Disease (PKD). With the enlargement of the cysts, they will oppress the normal renal tissues leading to renal ischemia and anoxia as well as low blood perfusion. Therefore, the blood pressure will rise. If uncontrolled, the renal high blood pressure in Polycystic Kidney Disease (PKD) will cause further pathological injury to kidneys resulting in renal fibrosis and elevated creatinine level. In return, the aggravation of the disease will cause the blood pressure to rise again, which may cause heart enlargement and even heart failure.
Now you are in the stage 4 of CKD. Please don't worry, in this stage, the kidney repair can be reversed.
For your illness condition, our hospital mainly use Herbal medicines , and other adjuvant therapies, like Chinese Herb Bath, acupuncture and so on.
The well-chosen medicines are shattered into powder and then are packed in bags made of special material. Then with the help of modern instrument, the effective medicine integrants will be able to be permeated into the kidney lesions directly from kidney area.
Then the effective medicine can work on the cysts and promote the resorption ability of the lining wall of the cysts. As a result, the cysts will stop growing and shrinking gradually.
Moreover, the medicine can dilate blood vessels to improve systemic blood circulation and increase the blood and nutrients supply to kidneys. Therefore, it can promote the self-repairing of the impaired renal functional cells due to oppression of the enlarged cysts

Serum Creatinine from 2-4, Flank Pain, Enlarged Kidneys

Illness description: The serum creatinine was 2 before, but now it is 4, is this due to the cysts of PKD? The right kidney measures 174mm*91mm and left kidney measures 174mm*85mm. At present,My father is having pains in lower side of waist, what could be the reason?
Illness analysis: now, the cysts should be treated first, otherwise, the cysts may cause more damage to kidney
Both kidneys have enlarged so much and his serum creatinine is also very high. It suggests he is in stage 4 kidney disease. If not treated in time, he may have to start dialysis. His waist pain can be caused by two reasons. The pull force of the enlarging cyst walls will cause waist pain. Too much protein leakage will cause lack of protein supply for the musles, so he may have dull pain. If his pain is serious, he may have infection inside the cyst or kidney stone which is often the complication of ADPKD. If he doesn't have edema, I suggest he drink more water.
This kind of disease cannot be cured fundamentally, however we can shrink the cysts, increase the blood flow in the kidneys and improve the kidney function so as to avoid kidney failure and dialysis. We have to do something, not waiting passively for kidney failure.
We are the largest kidney disease specialized hospital in China and over 6.4% of our patients are with PKD. The treatment I recommend are herbal medicines and "Duo Nang Xiao".
Herbal medicines is a conservative therapy without pumping fluid or relieving pressure. It is a kind of external application on the back. The Chinese medicine are micronized into one thousandths of its original size. With the action of the microwave, the medicine will permeate into the renal lesions directly through the skin and channels. We use Herbal medicines to expand blood vessels, speed up blood circulation on cysts walls, and improve the permeability of the cysts thus making the cysts shrink and decrease. It will restrain the proliferation of the epithelial cells, so the secretion of cyst liquid will be reduced. When the internal pressure of the cyst declined, the size of the cyst will gradually become smaller, thus relieving the compression of the tissues around, improving microcirculation, and blocking the progressing of renal fibrosis. Besides, the cysts are not easy to recur after disappearance, and the symptoms will thoroughly disappear. The kidney function will also be better.
"Duo Nang Xiao" is a kind of oral taking medicine prescribed by Chinese medicine professor. It is effective in shrinking the cysts according to the clinical observation.
If you have his test reports, I hope you can send to me. I will analyze it and give you specific advice.
According to our former conversation, you said your father's kidneys are 170mm. That's really big. Even his serum creatinine is lowered down, his kidney function is continuing declining if the cysts are not treated. The enlarging of the cysts will press the around kidney tissues and cause lack of blood and oxygen supply in the kidneys. Once the renal fibrosis starts, it is hard to stop it. Therefore, on diet he has to avoid spicy food, greasy food, sea food and strong tea or coffee. These things are stimulating, which may enlarge the cysts.

PKD, Kidney Function of 17

Illness description: my father has PKD and high blood pressure. My creatinine is very high now and i have at present about 17 kidney functions left. Is it too late for me to treat the disease?
Illness analysis: your father is at present in stage 4 CKD according to his remaining kidney functions, but kidney function of 17 is very close to end stage PKD, therefore timely and proper treatments and home nursings are very necessary for him.
Since the GFR is already very low, doctors usually will give suggestions for dialysis according to GFR level, when it decreases to 15, dialysis will be prepared. So regular tests should be done, to examine and follow your disease progress. And there is any discomforts, you should pay attention, and consult your doctor.
The external application of herbal medicines, as you said, will be needed every day, and 2-3 times per day. These medicines are mainly to treat your cysts, to shrink them. The medicines can arrive at the kidney lesions with the urinary bladder channel, in Chinese medicine, and then act on the lining cells of the kidneys, to restrain the secretion of the cystic fluid, and also increase the permeability of the cyst wall, so the fluid can be discharged out more quickly. From these two ways, the cysts will get smaller and smaller. And the pressure caused by the enalrging cysts will be lessened. And the Chinese medicines is known as treating disease from the root, but it also has low effects, so after your condition become stable, you still need take some medicines home for consolidation treatments.
Your kidney function is very low now, and is near end stage of kidney failure, so we suggest you take cell therapy, to improve the kidney function.
There are some countries to cell therapy at present, but for PKD patients, our chinese medicines take an important role in the treatments for PKD. And for such patients, not a single treatment can improve the patient's condition. We need to combine western medicines, chinese medicines, and cell therapy, and sometimes we still need blood purification methods, together to let the patient's condition become better.
And for the payment, i am not so clear about the procedure in your country, but in China, if we go to a hospital, we need to deposit some money first, to do some tests, some initial treatments, etc. and then like, if patient needs to do a surgery, they need to pay the money first for the surgery, then the doctors will do it for the patient. That's how it works in China. So after you come, you also need to pay some deposit money first, and then, if treatment plan is made for you, you need to pay the money before the treatment starts. Hope you can understand this procedure. IF not, you can tell me, and i will explain it again.
For PKD patients, we have treated many cases, and we also had a survey, about the patients who are treated in our hospital, about their complications, you can read it. For PKD, of course, in every stage, the results will be different. We have some patients, who are treated in early stage, they are still keeping a good kidney function now. And for some later stage patients, if they haven't started dialysis, the treatments can maintain the current condition. And for some end-stage patients, after the treatments, their dialysis may be reduced gradually. So different conditions will have different results. And of course, the whole process needs the cooperation of the patients with our doctors. Then it will achieve the best result.

Early Stage PKD, Basic Knowledge of PKD

Illness description: i recently found that i have Polycystic kidney disease and both my father and cousin have it too. Both my kidneys have renal cysts and my right kidney is a bit bigger than the left one. But my kidney functions are normal and i have no started dialysis yet. So far that is all i know. I want to know some basic knowledge about PKD and the more the better.
Illness analysis: Please don't worry , PKD is a very common kidney disease , if you can treat it timely , your renal function can be protected well .
Polycystic kidney disease (PKD or PCKD, also known as polycystic kidney syndrome) is a cystic genetic disorder of the kidneys There are two types of PKD: autosomal dominant polycystic kidney disease (ADPKD) and the less-common autosomal recessive polycystic kidney disease (ARPKD).
It occurs in humans and some other animals. PKD is characterized by the presence of multiple cysts (hence, "polycystic") typically in both kidneys; however 17% of cases initially present with observable disease in one kidney, with most cases progressing to bilateral disease in adulthood.The cysts are numerous and are fluid-filled, resulting in massive enlargement of the kidneys. The disease can also damage the liver, pancreas and, in some rare cases, the heart and brain. The two major forms of polycystic kidney disease are distinguished by their patterns of inheritance.
As for PKD there is one pathogenetic regularity , generally when the patients are in 30 years old , their blood pressure will be higher ,in 40 years old their creatinine level will be higher , in 50 years old there will be renal failure .
The most common symptoms are pain in the back and the sides (between the ribs and hips), and headaches. The dull pain can be temporary or persistent, mild or severe.
People with autosomal dominant PKD also can experience the following complications:
· Urinary tract infections, specifically in the kidney cysts
· Hematuria (blood in the urine)
· Liver and pancreatic cysts
· Abnormal heart valves
· High blood pressure
· Kidney stones;
· Aneurysms (bulges in the walls of blood vessels) in the brain
· Diverticulosis (small pouches bulge outward through the colon).
Proper diets for early stage PKD
Add Flax Oil to Your Meals
Flax seed oil has also been show to help ease the symptoms of PKD. (Ogborn, M.R., et al. "Flaxseed ameliorates interstitial nephritis in rat polycystic kidney disease." Flax oil is an excellent source of a group of fatty acids (omega-3-fatty acids) that are thought to have anti-hypertensive, lipid-lowering and anti-inflammatory effects. All of these benefits can help with polycystic kidney disease.

PKD and High Blood Pressure

High blood pressure is one of the common clinical manifestations of polycystic kidney disease, polycystic kidney disease early clinical manifestations. Foreign reports polycystic kidney disease in patients with blood pressure higher than the general population as early as ten years, 60% of patients in the renal blood pressure abnormalities before. Into ESRD stage, almost all patients with hypertension. Polycystic kidney disease is similar to other types of kidney disease, high blood pressure is an important factor to affect the progression of renal function, is also a major risk factor for cardiovascular complications.
Polycystic kidney disease, high blood pressure causes a great relationship with cyst size of the patient's body. Reduced local blood flow the increased cyst growing oppression of certain blood vessels in the kidney, and kidney receptors feel this reflex to a signal renin production increased, and thus the angiotensin concentration vasoconstriction caused by high blood pressure, But after the Chinese medicine, can be lifted compression symptoms of the cyst surrounded kidney unit, mitigation normal renal tissue ischemia missing oxygen, slow down the process of renal fibrosis. This will not only ease the generation of high blood pressure, and with vascular tone factor release weakened, increased vasodilator, promote blood circulation of the wall, the blood vessel becomes a degree of relaxation. blood pressure will be gradually manipulation. treatment of polycystic kidney disease, a series of clinical studies, but the most viable clinical interventions or polycystic kidney disease in patients with blood pressure control.
Strict control of blood pressure, heart and kidney function is essential for protection of polycystic kidney disease patients. Antihypertensive drug treatment should be early, the vast majority of drug therapies available to good results. ACEI, ARB, the ideal preferred drugs, and other commonly used drugs, calcium channel antagonists, beta blockers and central antihypertensive drugs.
Polycystic kidney failure patients should maintain freshness mood, work and rest, and establish the confidence to overcome the disease with treatment. Should the novelty usual diet, and nutritious, eat more fruits, appropriate manipulation protein intake, Eat cold Feigan of the goods or spicy, quit alcohol, to maintain smooth stool. Hypertension edema is significant, should be limiting sodium intake. May be appropriate to participate in a number of sports and entertainment activities, but it should prevent the waist and abdomen extrusion collision, to avoid cyst rupture. Patients with severe illness should stay in bed.

Will Polycystic Kidney Disease Develop Kidney Failure

Polycystic kidney disease is a chronic kidney disease and it takes relatively longer time to develop into end stage renal disease especially if patients have timely and effective treatments and home nursing measures, even though, the risk still exists.
When PKD develops into renal failure, it will have all the symptoms and complications of chronic kidney failure besides some special symptoms of renal cystic diseases like abdominal masses, fluid-filled sacs forming in kidneys.
The symptoms and complications when PKD develop into renal failure:
Water, electrolyte and acid-base metabolism disorders
Chronic renal failure, acid-base balance and electrolyte metabolism disorders are quite common. Electrolyte balance disorder is the most common type of metabolic disorders, metabolic acidosis and water.
(1) metabolic acidosis in patients with mild to moderate chronic renal failure (GFR> 25ml/min, or serum creatinine <350 μmol / l) in some patients due to renal tubular secretion of hydrogen ions obstacles or tubular HCO3-heavy absorption capacity decreased, thereby causing renal tubular acidosis. When GFR decreased to <25ml/min (serum creatinine> 350μmol / l), renal failure metabolites such as phosphoric acid, sulfuric acid and other acidic substances due to renal excretion obstacles retention can occur uremic acidosis. Mild chronic acidosis, the majority of patients with fewer symptoms, such as arterial HCO3-<15 mmol / L, you can appear obvious loss of appetite, vomiting, weakness, breathing deep.
(2) water-sodium metabolism, mainly Shuinazhuliu, or hypovolemic hyponatremia. Renal insufficiency, renal sodium load too much or excess capacity, the ability to adapt gradually decreased. Shuinazhuliu can be expressed varying degrees subcutaneous edema and / or body cavity effusion, which is quite common in clinical; prone to high blood pressure, left ventricular dysfunction (chest tightness, activity decreased resistance even at night not supine) and brain edema. The hypovolemic performance for low blood pressure and dehydration. Hyponatremia reasons, both cause (authenticity hyponatremia) due to a lack of sodium and too much water, or other factors caused by (False hyponatremia), while the latter is more common.
(3) potassium metabolism disorders: when the GFR reduced to 20-25ml/min or lower, renal potassium row capacity decreased, is prone to hyperkalemia; especially when excessive potassium intake, acidosis, infection, trauma, gastrointestinal bleeding occurs more hyperkalemia. There is a certain danger of serious hyperkalemia (serum potassium> 6.5mmol / l), the need for timely treatment to rescue. Sometimes inadequate potassium intake, gastrointestinal excessive loss of potassium-sparing diuretics and other factors, application row hypokalemia.
(4) calcium and phosphorus metabolism, mainly for of phosphorus too much and calcium deficiency. Calcium deficiency primarily with calcium intake, lack of active vitamin D, hyperphosphatemia, metabolic acidosis related to a variety of factors, the obvious lack of calcium, hypocalcemia can occur. "Phosphate regulating intestinal absorption and renal excretion of phosphorus. When the glomerular filtration rate, urinary discharge to reduce serum phosphate levels gradually increased. In the early stage of renal failure, serum calcium, phosphorus still remained in the normal range, and usually does not cause clinical symptoms appear only in late stage of renal failure (GFR <20ml/min) hyperphosphatemia, hypocalcemia hyperlipidemia. Hypocalcemia, hyperphosphatemia, active vitamin D deficiency can be induced by elevated parathyroid hormone (PTH), secondary hyperparathyroidism (referred to as hyperparathyroidism) and renal osteodystrophy.
(5) magnesium metabolism disorders: when GFR <20ml/min reduction in kidney platoon magnesium, often mild hypermagnesemia. Patients often no symptoms; such as the use of magnesium-containing drugs (antacids, laxatives, etc.), are more prone. Hypomagnesemia can occur even magnesium intake is insufficient or excessive application of diuretics.
Metabolic disorders of protein, carbohydrates, fats, and vitamins
The CRF protein metabolism in patients with general performance of the protein metabolite accumulation (azotemia), serum albumin levels, essential amino acids in plasma and tissues levels. Metabolic disorders with protein decomposition increased or / and reduce the synthesis of negative nitrogen balance, the renal excretion disorders and other factors related to.
Abnormal glucose metabolism mainly manifested as impaired glucose tolerance and hypoglycemia both cases, the former is more common, which is rare. Hyperlipidemia is quite common, and most of the patients showed mild to moderately high hypertriglyceridemia, a small number of patients showed mild hypercholesterolemia, or both. Vitamin fairly common metabolic disorders, such as increased serum levels of vitamin A, vitamin B6 and folic acid deficiency.
Cardiovascular system
Cardiovascular disease is one of the major complications of CKD patients and the most common cause of death. Especially into ESRD stage, the mortality rate is increased further (uremia cause of death in 45% -60%). Recent studies have found that uremic patients with adverse cardiovascular events and artery atherosclerotic cardiovascular disease about 15-20 times higher than the general population.
More common cardiovascular disease, hypertension and left ventricular hypertrophy, heart failure, uremic cardiomyopathy, pericardial effusion, pericarditis, vascular calcification and arterial atherosclerosis, etc.. In recent years, found that hyperphosphatemia, calcium abnormal distribution and vascular protective proteins (such as fetuin-A) caused by a lack of vascular calcification, also plays an important role in cardiovascular disease.
Respiratory symptoms
Fluid overload or acidosis can be shortness of breath, shortness of breath, severe acidosis can cause breathing deep. Fluid overload, heart failure can cause pulmonary edema or pleural effusion. Alveolar capillary permeability induced by uremic toxins can cause lung congestion uremic pulmonary edema, chest x-ray examination at this time, there may be a "butterfly-wing" levy, timely diuresis or dialysis of the above symptoms can rapidly improve.
Gastrointestinal symptoms
Mainly loss of appetite, nausea, vomiting, oral Niaowei. Gastrointestinal bleeding are more common, and its incidence is significantly higher than normal, mostly due to the gastric mucosal erosions or peptic ulcer, especially in the former is the most common.
Blood system performance
CRF patients with abnormal blood system mainly for renal anemia and bleeding tendency. Most patients generally have light, moderate anemia, the reason is mainly due to erythropoietin lack, it is known as renal anemia; such as accompanied by iron deficiency, malnutrition, bleeding, and other factors that may aggravate the degree of anemia. Late CRF patients with bleeding tendency, such as subcutaneous or mucous membrane bleeding, petechiae, gastrointestinal bleeding, cerebrovascular bleeding.
Neuromuscular symptoms
Early symptoms may have insomnia, difficulty concentrating, memory loss. Uremia indifferent response, delirium, convulsions, hallucinations, coma, and mental disorders. Peripheral neuropathy is very common, more significant sensory nerve disorder, the most common is the loss of sensation in extremities sock-like distribution, can also be numbness, burning sensation or pain, deep reflection slow or disappear, and may have neuromuscular increased excitability, such as muscle tremors, spasms, restless legs syndrome. The initial dialysis patients dialysis disequilibrium syndrome may occur, appear as nausea, vomiting, headache, convulsions, mainly due to the intracellular and extracellular fluid osmotic imbalances and brain edema after hemodialysis, caused by increased intracranial pressure.
Endocrine dysfunction
Mainly: (1) kidney itself endocrine dysfunction: 1,25 (OH) 2 vitamin D3, erythrocyte erythropoietin and intrarenal renin angiotensin tangled II too much; ② hypothalamic-pituitary endocrine dysfunction: such as lactation hormone, melanocyte hormone (MSH), luteinizing hormone (FSH), follicle-stimulating hormone (LH), promoting increased levels of the adrenal cortex hormone (ACTH): ⑧ outside weeks of endocrine disorders: Most patients had serum PTH liter high, some patients (about a quarter) a mild lower thyroid hormone levels; well as insulin receptor disorder, hypogonadism.
Bone lesions
Renal osteodystrophy (renal osteodystrophy) is fairly common, including fibrocystic osteitis (high-turnover bone disease), poor bone formation (adynamic bone disease) and osteomalacia (low-turnover bone disease) and bone quality osteoporosis. Approximately 35% of the abnormal bone X-ray found in pre-dialysis patients, but bone pain, difficulties in walking and spontaneous fractures are quite rare (less than 10%). Abnormal bone biopsy (bone biopsy) of approximately 90%, early diagnosis is to rely on bone biopsy.
Fibrocystic osteitis is mainly caused by excessive PTH prone bone salt dissolves, rib fractures. X-ray examination showed bone cystic defects (such as the phalanx, ribs) and osteoporosis (such as the spine, pelvis, femur, etc.) performance.
Adverse occurrence of bone formation, serum PTH concentration is relatively low, some osteogenic factors related to insufficient and therefore not sufficient to maintain bone regeneration; dialysis patients, such as long-term excessive application of the active form of vitamin D, calcium, and other drugs or dialysate calcium content High, you can make relatively low concentrations of serum PTH.